Actualités en direct des projets (non traduites)

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Dear participants,

We wish you a merry Christmas and a happy New Year!

With your help, we have performed a lot of computer modeling. We are going to continue, and believe the results will lead to advances in drug development! For now, we have a fresh new release of CmDock and will employ it starting from the next target. Here is an illustration of the modeling performed in the project, visualized with PyMOL. You can see a large molecule (this is the target, TMPRSS2 protein) with a molecule many times smaller. The small molecules are ligands, each of them can interact with the target in its own way, with its own binding energy.

The more precisely the ligand binds to the target, the higher the chance that it will be able to change the functioning of the large molecule. For example, the TMPRSS2 enzyme shown in the image is necessary for a chemical reaction allowing the coronavirus to enter the body cells and, accordingly, a substance that can suppress the normal operation of this enzyme can make it difficult or block the spread of the coronavirus in it. During the modeling performed on your computers, various ligands from the library are tested, and the best ones are selected to process on next stages of drug development.

All the best,
Natalia, Marko, hoarfrost, ÄŒrtomir



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Création : 24 décembre 2022

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Aliquot sequence 103^62 has terminated!!!



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Création : 24 décembre 2022

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Dear Crunchers of this project. Let me wish you merry christmas and happy winter solstice. It weights my hearth to write this message, but things had come to a point where it is better to end things, rather than endlessly drag them out to no end. Since the summer, I have been hopelessly stomped by a stream of activity, both happy and necessary. It turned out to be impossible to care about this project. Even thought it almost runs itself, even thought I'm thinking right now "gosh, it really should be possible to find a hour or two each month".
It is time to announce that this project will no longer provide any compute jobs. I will, of course, keep the site running, but since there is no work, no new users can get enough points to post, the forums will effectively be dead.

Best regards, Veronika.

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Création : 24 décembre 2022

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for Windows and Linux, to enable it in your prefs, choose Intel

This is still in test to tweak the plan_class to get work. Iam hoping to avoid Intel HD Graphics if you have both onboard.

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Création : 24 décembre 2022

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https://www.mersenneforum.org/showthread.php?t=28328

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Création : 23 décembre 2022

Détails

To collect some datas for the devs we need some testers with Intel ARC GPUs.

What todo?

Run mfakto --perftest on windows, linux is a bit different somewhere standalone on your PC and post the output here.

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Création : 22 décembre 2022