Actualités en direct des projets (non traduites)

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Création : 19 mars 2022

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With almost 2.5 million years of scientific computations, the amazing WCG volunteers contributed to 32 scientific projects already.

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Création : 18 mars 2022

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SRBase was choosen. I missed the info before so there will be more work soon.

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Création : 18 mars 2022

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The second challenge of the 2022 Series will be a 5-day challenge in celebration of World Water Day, the annual United Nations Observance, started in 1993, that celebrates water and raises awareness of the 2 billion people currently living without access to safe water. The challenge will be offered on the 321-LLR application, beginning 21 March 03:21 UTC and ending 26 March 03:21 UTC. To participate in the Challenge, please select only the 321 Prime Search LLR (321) project in your PrimeGrid preferences section. For more info and discussion, check out the forum thread for this challenge: https://www.primegrid.com/forum_thread.php?id=9888&nowrap=true#154866

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Création : 17 mars 2022

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While we are moving to a new location, we take a look into the major changes that took place in WCG history

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Création : 14 mars 2022

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Dear SiDock@home community,

Here is an update on our work. This international scientific drug
discovery project is well on its way towards its first milestone of
experimental support for the docked compounds. We are working hard
towards data processing and scientific collaborations that can help us
take our proposed compounds further. In the near future, we will prepare
a scientific write-up for You to follow.

This international drug discovery project is a wonderful example of
community, citizen science, teamwork, and contributing to the field of
medicinal chemistry with the ultimate goal of contributing to the
wellbeing of us all. Our heart goes out to all!

We also thank You for the help and support that keeps us going.
Currently, our servers reside in Russia and Slovenia. This enables us
easier task allocation and backup of the results and we hope to add a
third location with additional hardware in the future. Due to the
community request, we also plan to add official Mac and ARM64 support
for the underlying CmDock software.

Moreover, we are continuing with a new target, still from the SARS-CoV-2
pathogen, namely nsp14. It consists of the N-terminal ExoN domain
involved in proofreading and the C-terminal guanine N7 methyl
transferase (N7-MTase) domain that functions in mRNA capping and on the
latter we are focusing on now.

After this target is complete, we are turning our attention towards one
potential therapeutic target of the Ebola viral pathogen to return back
to SARS-CoV-2 after that target will be complete.

We are committed to this drug discovery project and the online
community, hope to expand and we look forward to working and discovering
new molecules and compound mechanisms of action in the future.

All health, luck, and peace to all!
Marko Jukic

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Création : 14 mars 2022