Actualités en direct des projets (non traduites)

Détails

Dear participants!

The work by upgrade is completed. Project database, website and request processing migrated on pair of mirrored SSD, workunit files (as previously) and uploaded results placed on mirrored HDD.

Thank you for attention and participation!

Source

Création : 17 février 2022

Détails

Hello! Additional server maintenance planned on February 15th, for several hours. Approx. 08:00-20:00 UTC.

Source

Création : 15 février 2022

Détails

Hello! Additional server maintenance planned on February 15th, for several hours.

Source

Création : 14 février 2022

Détails

Dear all,

On February 14th, for about 08:00-20:00 UTC, the project server will be shut down for maintenance. We will upgrade hard drives to support larger loads.

All the best,
Team SiDock@home

Source

Création : 11 février 2022

Détails

In the near future (today or tomorrow) there may be an unannounced downtime of the server. It should not last longer than an hour and is related to the change of some disks on the main project server.
We do not expect any loss of job, the whole thing should last no more than an hour.

Source

Création : 11 février 2022

Détails

Dear Participants,

We continue diligently with the calculations. Now we are breaking through a series of protease studies to explore a new target, the RBD (receptor-binding domain) Sprot domain surface interacting with ACE2. This is the much-discussed spike protein that also contributed to the naming of coronavirus. We focus here on Sprot from the delta variant (B.1.617.2), specifically a Cryo-EM structure of Sprot with an RBD in up conformation. In comparative variant studies, we will try to determine if there is a specific discrimination upon binding of small ligands. This may help us better understand this PPI surface in further studies and even develop a small molecule probes to study these interactions.
Thank You all and we look forward to future studies together!

With best wishes,
Team SiDock@home

Source

Création : 10 février 2022