Actualités en direct des projets (non traduites)

Détails

Hello! Additional server maintenance planned on February 15th, for several hours. Approx. 08:00-20:00 UTC.

Source

Création : 15 février 2022

Détails

Hello! Additional server maintenance planned on February 15th, for several hours.

Source

Création : 14 février 2022

Détails

Dear all,

On February 14th, for about 08:00-20:00 UTC, the project server will be shut down for maintenance. We will upgrade hard drives to support larger loads.

All the best,
Team SiDock@home

Source

Création : 11 février 2022

Détails

In the near future (today or tomorrow) there may be an unannounced downtime of the server. It should not last longer than an hour and is related to the change of some disks on the main project server.
We do not expect any loss of job, the whole thing should last no more than an hour.

Source

Création : 11 février 2022

Détails

Dear Participants,

We continue diligently with the calculations. Now we are breaking through a series of protease studies to explore a new target, the RBD (receptor-binding domain) Sprot domain surface interacting with ACE2. This is the much-discussed spike protein that also contributed to the naming of coronavirus. We focus here on Sprot from the delta variant (B.1.617.2), specifically a Cryo-EM structure of Sprot with an RBD in up conformation. In comparative variant studies, we will try to determine if there is a specific discrimination upon binding of small ligands. This may help us better understand this PPI surface in further studies and even develop a small molecule probes to study these interactions.
Thank You all and we look forward to future studies together!

With best wishes,
Team SiDock@home

Source

Création : 10 février 2022

Détails

Hey Everyone,

It's finally that time! The southern sky runs from before have converged, and it's time to start new ones while we dig through all that data.

I have taken down the following runs:

de_modfit_84_bundle4_4s_south4s_gapfix
de_modfit_84_bundle4_4s_south4s_gapfix_bgset2
de_modfit_84_bundle4_4s_south4s_gapfix_bgset3
de_modfit_85_bundle4_4s_south4s_gapfix
de_modfit_85_bundle4_4s_south4s_gapfix_bgset2
de_modfit_85_bundle4_4s_south4s_gapfix_bgset3

And I have put up the following runs:

de_modfit_70_bundle5_3s_south_pt2
de_modfit_71_bundle5_3s_south_pt2
de_modfit_72_bundle5_3s_south_pt2
de_modfit_73_bundle5_3s_south_pt2
de_modfit_74_bundle5_3s_south_pt2
de_modfit_75_bundle5_3s_south_pt2
de_modfit_76_bundle5_3s_south_pt2
de_modfit_77_bundle5_3s_south_pt2
de_modfit_78_bundle5_3s_south_pt2
de_modfit_79_bundle5_3s_south_pt2
de_modfit_80_bundle5_3s_south_pt2
de_modfit_81_bundle5_3s_south_pt2
de_modfit_82_bundle5_3s_south_pt2
de_modfit_83_bundle5_3s_south_pt2
de_modfit_84_bundle5_3s_south_pt2
de_modfit_85_bundle5_3s_south_pt2
de_modfit_86_bundle5_3s_south_pt2

The workunits from the old runs will continue to go out for a little while while results and validations trickle in to the server. You should see workunits from the old runs go away within a week or so. Please let me know if you have any issues with these runs. With any luck the 7-size workunit problem should disappear.

Thanks for the continued support, and happy crunching!

-Tom

Source

Création : 9 février 2022